Hyperleukocytosis: A Rare Manifestation of Autoimmune Hemolytic Anemia


Autoimmune hemolytic anemia (AIHA) is described by destruction of Red Blood Cells (RBCs) as a result of binding of antibodies to red blood cell surface antigens. White blood cells are usually normal and hyperleukocytosis is rare. The most common microorganism that has been associated with these hemolytic processes is Mycoplasma pneumoniae. We presented a case study, a 4-year-old boy child who was diagnosed AIHA by warm antibody testing with high leukocyte count. The patient was treated with methylprednisolone, intravenous immunoglobulin and clarithromycin. During treatment, the leukocytosis became normal. The clinical condition and vital signs improved. The purpose of this study was to highlight hyperleukocytosis in AIHA caused by Mycoplasma pneumoniae.

Keywords: Autoimmune Hemolytic Anemia, Child, Leukocyte, Mycoplasma.


Volume 9 Issue-4 2020
DOI : https://doi.org/10.36283/PJMD9-4/016
Publisher Name : Ziauddin University
  • Ilknur Uzunoglu
  • Nursima Cukadar
  • Egemen Tavrak
  • Elif Suleymanoglu
    • Department of Pediatrics, Health Science University, Kartal Dr. Lütfi Kırdar Şehir Hastanesi, Istanbul, Turkey
  • Sema Yilmaz
    • Department of Pediatrics Hematology and Oncology, Kartal Dr. Lütfi Kırdar Şehir Hastanesi, Istanbul, Turkey.